For donor-sperm IUI, prepared sperm are placed into the uterus around ovulation. Monitoring and whether medicines are needed depend on the recipient’s circumstances. IVF may be considered instead when tubal disease, other fertility factors or the treatment history makes insemination unsuitable. During IVF, eggs are fertilised with sperm in the laboratory. ICSI, which involves injecting a sperm into an egg, may be appropriate for particular indications, but is not routinely better for everyone using donor material.
Donor-egg treatment involves coordinating egg availability, fertilisation and preparation of the recipient for embryo transfer. Donor embryos, if a lawful pathway is confirmed, require appropriate records, consent and recipient preparation before transfer. The timing may involve fresh or previously frozen material, depending on the actual arrangement. Some eggs or embryos may not survive freezing and warming, and development may stop before transfer. Even when fertilisation occurs through IVF or ICSI, implantation and live birth are not guaranteed.